A war going on for centuries between vampires and Lycans/werewolves, never seen by humans eyes, until one of the werewolves by the name of Lucian (Michael Sheen) finds out about one human that can bond with vampire blood and Lycans blood, Michael (Scott Speedman). Selene (Kate Beckinsale) is the vampire Death dealer that finds out why the Lycans are following Micheal and falls in love with him. Kraven (Shane Brolly) is the leader of the vampire house after Viktor (Bill Nighy) dies and wants Selene by his side, but she is a wild cat to break.
This movie continues the saga of war between the Death Dealers (vampires) and the Lycans (werewolves). The film traces the beginnings of the ancient feud between the two tribes as Selene (Kate Beckinsale) and Michael (Scott Speedman), the lycan hybrid, try to discover the secrets of their bloodlines. All of this takes them into the battle to end all wars as the immortals must finally face their retribution.